Endothelin Receptor
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Endothelin Receptor Inhibitors
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Endothelin Receptor Agonists
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Endothelin Receptor Antagonists
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Endothelin Receptor Modulator
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Endothelin Receptor Control
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Endothelin Receptor Ligands
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Endothelin Receptor Related Products (95)
Related Products (95)
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Kendomycin
0 ImagesCat. No.: HY-121300CAS No.: 183202-73-5Synonyms: (-)-TAN2162Kendomycin ((−)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent.
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Sarafotoxin S6c
0 ImagesSynonyms: SRTX-cSarafotoxin S6c (SRTX-c) is a potent endothelin-B receptor agonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels.
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Macitentan n-butyl analogue
0 ImagesMacitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
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H-Trp-Phe-OH
0 ImagesH-Trp-Phe-OH (Trp-Phe) is an ACE inhibitor and endothelial function regulator, with an ACE IC50 of 0.318 mg/mL. H-Trp-Phe-OH increases nitric oxide concentration, reduces endothelin-1 (ET-1) levels, and reverses norepinephrine-mediated endothelial cell dysfunction. H-Trp-Phe-OH exhibits antihypertensive activity. H-Trp-Phe-OH can be used in studies related to hypertension and atherosclerosis.
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BQ-3020 ammonium
0 ImagesCat. No.: HY-P1016BPurity: 98.96%BQ-3020 ammonium is a selective endothelin receptor (ETB receptor) agonist. BQ-3020 ammonium inhibits [125I] ET-1 binding to ETB receptors, with an IC50 value of 0.2 nM. BQ-3020 ammonium elicits vasoconstriction in the rabbit pulmonary artery. BQ-3020 ammonium makes relaxation of the pig urinary bladder neck and can be used for cardiovascular disease research. .
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Enrasentan
0 ImagesSynonyms: SB 217242Enrasentan (SB 217242) is an endothelin (ET) receptor antagonist. Enrasentan has antihypertensive effects.
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Endothelin-2 (49-69), human
0 ImagesSynonyms: Endothelin-2 (human, canine); Human endothelin-2Endothelin-2 (49-69), human (Endothelin-2 (human, canine)) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
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Carperitide
0 ImagesCat. No.: HY-P1235CAS No.: 89213-87-6Synonyms: Atrial Natriuretic Peptide (ANP) (1-28), human, porcineCarperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) inhibits endothelin-1 secretion in a dose-dependent way.
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TAK 044
0 ImagesCat. No.: HY-105168CAS No.: 157380-72-8TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage.
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Diosuxentan
0 ImagesCat. No.: HY-153463CAS No.: 2305865-93-2Synonyms: SC0062Diosuxentan is an inhibitor of ETA. Diosuxentan can be used in research for cardiovascular, renal and neuronal inflammation diseases.
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Macitentan (Standard)
0 ImagesSynonyms: ACT-064992 (Standard)Macitentan (Standard) is the analytical standard of Macitentan. This product is intended for research and analytical applications. Macitentan (ACT-064992) is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
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BQ-123 TFA
0 ImagesCat. No.: HY-12378ABQ-123 TFA is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 TFA inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension.
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Bosentan-d4
0 ImagesCat. No.: HY-115417CAS No.: 1065472-77-6Bosentan-d4 is the deuterium labeled Bosentan. Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
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(Rac)-Ambrisentan-d3
0 ImagesCat. No.: HY-13209BSCAS No.: 1189479-60-4(Rac)-Ambrisentan-d3 is the deuterium labeled (Rac)-Ambrisentan.
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Sulfatroxazole-d4
0 ImagesCat. No.: HY-105829SSynonyms: Isosulfafurazole-d4Sulfatroxazole-d4 (Isosulfafurazole-d4) is the deuterium labeled Sulfatroxazole (HY-105829). Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC50 of 0.26 μM).
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[Ala1,3,11,15]-Endothelin (53-63)
![[Ala1,3,11,15]-Endothelin (53-63)](https://file.medchemexpress.com/product_pic/hy-p1019.gif "Click to View [Ala1,3,11,15]-Endothelin (53-63) Product Detail")
0 ImagesCat. No.: HY-P1019CAS No.: 121204-87-3[Ala1,3,11,15]-Endothelin (53-63) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) can be used for the research of vasoconstriction
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BMS-248360
0 ImagesCat. No.: HY-114953CAS No.: 254737-87-6BMS-248360 is a potent and orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor, with Kis of 10 nM and 1.9 nM for hAT1 and hETA receptor, respectively. BMS-248360 displays hypertensive effects.
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Methylsolfonyl 25(S)-Δ7-dafachronic acid
0 ImagesCat. No.: HY-157940Methylsolfonyl 25(S)-Δ7-dafachronic acid (compound 3) is a selective ssDAF-12 agonist with the IC50 of 0.41 μM. Methylsolfonyl 25(S)-Δ7-dafachronic acid shows low cell cytotoxicity in HepG2 cells with IC50 of >200 μM. Methylsolfonyl 25(S)-Δ7-dafachronic acid can be used for study of parasitism.
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TBC3711
0 ImagesCat. No.: HY-106182CAS No.: 349453-49-2TBC3711 is a endothelin receptor modulator, used for the research of endothelin-mediated disorders.
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[Lys4] Sarafotoxin S6c
![[Lys4] Sarafotoxin S6c](https://file.medchemexpress.com/product_pic/hy-p3563.gif "Click to View [Lys4] Sarafotoxin S6c Product Detail")
0 ImagesCat. No.: HY-P3563CAS No.: 1219444-22-0[Lys4] Sarafotoxin S6c, a sarafotoxin analogue, is a potent and partial agonist of endothelin receptor. [Lys4] Sarafotoxin S6c elicits contraction of pig coronary artery, with an EC50 of 1.5 nM.
